Orbitrap Astral Zoom

Hybrid quadrupole-Orbitrap-Astral system; High-speed HRAM MS/MS; Enhanced dynamic range and multiplexing

• Status: Active
• Country: USA
• Vacuum system : Three turbomolecular pumps + single dual-stage oil-free roughing pump; Enhanced vacuum for ultra-high Orbitrap performance
• Power Requirements and Consumption : 2× 208-230 V 15/16 A (instrument), 1× 200-230 V 16 A (pump), 1× 100-240 V 15/16 A (PC); ~1,400-1,500 W average
• Environmental requirements : 18-27 °C, 20-80 % RH non-condensing; Heat output ~5,200 BTU/h; Max temp fluctuation 0.5 °C/10 min
• Dimensions and Weight: 95.2 × 196.3 × 139.4 cm; 680.0 kg; without PC, pump, or options
• Analyzer type : Orbitrap/Quadrupole/Linear Ion Trap MS
• Scan modes : Full MS (Orbitrap), SIM, MS/MS in Orbitrap or Astral, Parallel Reaction Monitoring, DIA (Hybrid DIA), All Ion Fragmentation
• Mass range : Orbitrap: m/z 40 to 6,000 (standard), m/z 40 to 8,000 with BioPharma option; Astral: m/z 40 to 6,000
• High resolution : Yes
• Mass resolution/ Mass resolving power : Orbitrap: 7,500-480,000 FWHM at m/z 200; Astral Zoom: 80,000 FWHM at m/z 524 (TMT HR mode)
• Dynamic range : Orbitrap: > 5,000 (single microscan); Astral Zoom: > 1,000 (single microscan) with Enhanced Dynamic Range mode
• Sensitivity : Orbitrap: MS/MS 50 fg reserpine on-column S/N 100:1, SIM 50 fg reserpine on-column S/N 150:1; Astral Zoom: Low-Input Mode boosts single-ion detection probability by ~10% and peak area by ~73%
• Mass accuracy/Stability : Orbitrap: <3 ppm external, <1 ppm internal (24 h RMS drift); Astral Zoom: <5 ppm external (24 h RMS drift)
• Scanning speed : Astral Zoom: up to 270 Hz (with Bent Trap pre-accumulation); Orbitrap MS2: up to 40 Hz
• Dwell time : -
• MRM transition rate : -
• Polarity switching : Yes
• Fragmentation : HCD in Orbitrap or Astral
• Ion source types (LC-MS) : HESI (OptaMax NG), APCI optional, APPI optional